Plan B: Progestin-Only EC
Levonorgestrel 0.75 mg taken twice, 12 hours apart
(traditional, two-dose administration)
Unlabeled equivalent
20 pills/dose of Ovrette taken 12 hours apart
More effective/fewer side effects than Yuzpe
Data indicate a single dose of 1.5 mg levonorgestrel is as
effective and causes similar side effects as traditional two-
dose levonorgestrel
Mechanism of action is inhibition of ovulation
von Hertzen H, et al. Lancet. 2002;360:1803-1810.
Ellertson C. Fam Plann Perspect. 1996;28(2):44-48.
ACOG Practice Bulletin. Int J Gynecol Obstet. 2002;78:191-198.
Arowojolu AO, et al. Contraception. 2002;66:269-273.
Marions L, et al. Obstet Gynecol 2002;100:65-67.