Side Effects of EE 20 µg/LNG 100 µg (Alesse) vs.
Placebo: No Significant Difference
Alesse
Placebo
P-Value
Adverse
event
(n=349)
%
(n=355)
%
(Fisher’s
Exact)
Headache
31.5
30.1
.74
Nausea
14.0
11.3
.31
Weight gain
3.4
2.3
.37
Breast pain
4.6
3.1
.33
Hordinsky M et al.  8th World Congress of the International Society of Gynecological Endocrinology.
December 2000.  Florence, Italy.