Transport from the ER to the Golgi
When the protein is properly folded, COPII coated
vesicles transport the proteins via the vesicular tubular
cluster (vtc) to the cis-Golgi network.
The COPII coating is removed
(Sar1 hydolyzes GTP) and the
vesicles fuse with each other
to form the vtc.
The vtc is motored along
microtubules that function like
railroad tracks.
The vtc fuses with the cis-
Golgi network.